Dr. Scholl's One Step Callus Removers is medicated. Its patented formula contains salicylic acid USP 40% w/w and removes calluses effectively. It provides cushioning and pain relief from shoe pressure.Directions: 1. Wash affected area and dry thoroughly.2. Apply medicated cushion.3. After 48 hours , remove medicated cushion.4. Repeat procedure every 48 hours as needed for up to 14 days (until callus is removed)5. May soak callus in warm water for 5 minutes to assist in removal.Active ingredients: Salicylic acid 40%Inactive Ingredients: Antioxidant, hydrocarbon resin, iron oxides, mineral oil (heavy), precipitated silica, synthetic rubber, talc.