Dr. Perlmutter created this unique formula with 40 Billion CFU of beneficial probiotics, made from diverse strains that are resistant to stomach acid and bile, Zinc, and Vitamin DRecommended Dosage: Adults: Take 1 capsule daily with food, at least 2 3 hours before or after taking antibiotics, other medications or natural health products.Caution: Consult a health care practitioner prior to use if you have fever, vomiting, bloody diarrhoea or severe abdominal pain. Stop use and consult a health care practitioner if symptoms of digestive upset occur, worsen and/or persists beyond 3 days. Do not use this product if you have an immune-compromised condition.