Genestra Bio B12 + Folic Acid is a high dose B12 formula with folic acid. Provides 1000 mcg of vitamin B12 and 400 mcg of folic acid per dose

Bio B12 + Folic Acid includes a high dose of vitamin B12 to help support
macronutrient metabolism and prevent vitamin B12 deficiency.About B12 & Folic Acid: Vitamin
B12 is an important cofactor for two enzymatic reactions: methylmalonyl-CoA mutase, which helps break down branch chain amino
acids and odd numbered fatty acidsmethionine synthase, which is
needed for methyl transfer reactions, including the folic acid dependent
conversion of homocysteine to methionine for protein production.Daily
supplementation with 400 mcg of folic acid during the first trimester
helps decrease neural tube defects by approximately 50%. As folic acid
is a methyl group donor, research indicates that neural tube defects may
result from impaired methylation. Similarly, decreases in the
availability of vitamin B12 or folic acid lead to the accumulation of
homocysteine, which may inhibit methyl transfer reactions. Vitamin B12
helps enhance methionine synthesis and increases the ability of folic
acid to lower homocysteine levels for normal methyl metabolism. The
vitamin is also required for the methylation of proteins involved in the
synthesis and maintenance of myelin, and vitamin deficiencies can
result in decreased production of myelin sheath, material needed for
normal nervous system function. As methionine synthase is needed to
form red blood cells, deficiencies in vitamin B12 have been associated
with the production of abnormally large and irregularly shaped blood
cells.Recommended Dosage: (Adults and Children, 4 years and older): Chew one tablet daily, or as recommended by your healthcare practitioner. Caution: Do you use if outer seal is missing or broken. Store in a cool, dry place.